The level of harm that a substance can inflict to an organism is referred to as drug toxicity. A drug's toxicity is dose-dependent and can damage a whole system, such as the CNS, or a single organ, such as the liver. Toxicity refers to the extent to which a chemical substance or a mixture of chemicals can harm an organism. When bug or spider venom acts as a poison in the body, it causes a harmful reaction. This type of reaction can result from a single bite or sting from a very deadly bug or spider, or from several bites or stings from non-poisonous insects or spiders. Your age, weight, and overall health have an impact on the outcome. Poisoning might have short-term consequences, such as a rash or a mild sickness. It can result in brain damage, a coma, or death in severe situations. The most prevalent type of acute poisoning is ethanol intoxication, and the most common type of suicide by poisoning is medicinal medication overdose. Smoke inhalation or illegal drug usage are the most common causes of acute poisoning death. If this is the case, you may be placing yourself at danger of an overdose from an over-the-counter (OTC) pain reliever or fever medicine. When used as indicated, pain relievers are generally safe. Overdosing on these medications, however, can result in liver damage, gastrointestinal bleeding, and kidney illness.